Parkinson’s disease is a neurodegenerative disorder of the central nervous system characterized by hand tremors, muscle rigidity, slowness of movement, and impaired balance and coordination. Although the exact cause is still unknown, toxicity is believed to be the main culprit.
Cells in the brain, called neurons, are responsible for producing dopamine, a neurotransmitter that regulates movement. In Parkinson’s disease, these dopaminergic neurons in the substantia nigra die due to the accumulation of abnormal proteins.
Conventional treatment focuses on relieving symptoms and improving the patient’s quality of life. Some of the most commonly used methods include
Medications: Levodopa, Carbidopa, dopaminergic agonists, anticholinergics, etc.
Physical therapy: Exercises to improve flexibility, balance, and coordination.
Speech therapy: To improve articulation and swallowing.
Surgery: Deep brain stimulation in advanced cases.
VSELs (Very Small Embryonic-Like Stem Cells) are adult pluripotent stem cells with great potential for cell regeneration. These cells are found in the patient’s own bone marrow and adipose tissue, making them a safe, autologous option with a low risk of rejection.
Why VSELs?